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華蟾酥毒基

分析標(biāo)準(zhǔn)品,HPLC≥98%

Cinobufagin

CAS號：470-37-1

分子式：C26H34O6

分子量：442.55

MDL：MFCD00056825

產(chǎn)品介紹

熔點(diǎn)：222-223℃

沸點(diǎn)：595.4 ℃ at 760 mmHg

外觀：白色針晶

溶解性：易溶于氯仿、甲醇等有機(jī)溶劑，不溶于水。

儲存條件：2-8℃,避光

注意：部分產(chǎn)品我司僅能提供部分信息，我司不保證所提供信息的權(quán)威性，僅供客戶參考交流研究之用。

參考文獻(xiàn)(11篇)

11. [IF=3.4] Pin Wang et al."Exploring the mechanism of cinobufagin on gastric cancer based on proteomics, molecular dynamics, in vitro and in vivo experiment."TOXICOLOGY AND APPLIED PHARMACOLOGY.2025 Oct;503:117490

10. [IF=4.8] Hongxuan Yang et al."Huachansu suppresses colorectal cancer via inhibiting PI3K/AKT and glycolysis signaling pathways: Systems biology and network pharmacology."JOURNAL OF ETHNOPHARMACOLOGY.2025 Feb;:119479

9. [IF=7.9] Yi-Qing Deng et al."Compound-composed Chinese medicine of Huachansu triggers apoptosis of gastric cancer cells through increase of reactive oxygen species levels and suppression of proteasome activities."PHYTOMEDICINE.2023 Oct;:155169

8. [IF=3.889] Yaoyao  Bian et al."Cinobufagin induces acute promyelocytic leukaemia cell apoptosis and PML-RARA degradation in a caspase-dependent manner by inhibiting the β-catenin signalling pathway."PHARMACEUTICAL BIOLOGY

7. [IF=1.902] Ke-ke Cui et al."Quantitative analysis of multicomponents by a single marker and quality evaluation of Venenum Bufonis from different geographical origins."Biomed Chromatogr. 2019 Sep;33(9):e4555

6. [IF=4.379] Cao  Yueting et al."The impact of multiple climatic and geographic factors on the chemical defences of Asian toads (Bufo gargarizans Cantor)."Sci Rep-Uk. 2019 Nov;9(1):1-11

5. [IF=4.411] Yueting Cao et al."Chemical Profile and Multicomponent Quantitative Analysis for the Quality Evaluation of Toad Venom from Different Origins."Molecules. 2019 Jan;24(19):3595

4. [IF=2.193] Zhang Mei-Tuo et al."Strategic Combination of Isocratic and Gradient Elution for Simultaneous Separation of Polar Compounds in Traditional Chinese Medicines by HPLC."J Anal Methods Chem. 2018;2018:7569283

3.  張妹砣  李玉桑  葉曉雪. 六神丸血漿藥物化學(xué)的研究[J]. 綠色科技  2017  000(012):237-240.

2.  李志東  朱士春  葛朝暉. HPLC法測定不同批次麝香保心丸中華蟾酥毒基與脂蟾毒配基的含量[J]. 海峽藥學(xué)  2017  029(012):72-74.

1.  牛天力  秦國政. 華蟾酥毒基抑制人前列腺癌PC3細(xì)胞體外增殖研究[J]. 北京中醫(yī)藥大學(xué)學(xué)報(bào)  2018  41(12):53-58.

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